Taurine deficiency may be a factor in aging. study who evaluated the impact of the amino acid on health and longevity.

Fighting age-related taurine loss with dietary supplements breduction in the lifespan of rodents and primates and the conclusions justify further human trials.

Taurine is one of the most abundant amino acids in animals, and previous studies in various species have shown that taurine deficiency at an early age causes functional impairment in skeletal muscle, eyes, and the nervous system. Small clinical trials of taurine supplementation have shown benefits in metabolic and inflammatory diseases, but the effects of taurine concentrations on animal health and longevity remain poorly understood.

To better understand whether an abundance of taurine affects healthy lifespan, the researchers measured blood levels of taurine in mice, monkeys, and humans of all ages. They found that the concentration of taurine in the blood of 15-year-old monkeys was 85% lower than that of five-year-old monkeys. Similarly, taurine levels have dropped by more than 80% over the course of a person’s lifetime. A decrease in taurine levels was also observed in aging mice, and the researchers found that mice lacking the main transporter taurine had a shorter lifespan as adults..

Overcoming this decline with the addition of taurine increased the average lifespan of worms and mice by 10-23% and 10-12%, respectively. In mice, oral administration of taurine at doses of 500 and 1000 milligrams (milligrams) per kilogram of body weight per day has also been associated with improving strength, coordination and cognition and slowing down several key markers of agingincluding cellular senescence, mitochondrial damage and inflammation. In addition, they demonstrated that administering taurine to middle-aged rhesus monkeys had a positive effect on bone health, metabolism, and immune health.

Its authors research published in the journal Sciencenote that replenishing taurine deficiency during aging may be one of the promising anti-aging strategyhowever, further research and human clinical trials are needed to determine whether taurine supplementation increases healthy lifespan in humans. The possibility of risks must be considered as there are no large long-term safety trials in humans.

Source: RES