Alex De Minaur (18th seed) and Tommy Paul (29th seed) were beaten in the third round of the 2022 US Open.

Alex de MinaurPhoto: Daniel Varnado / AP – The Associated Press / Profimedia

De Minaur lost to Pablo Carreño-Busta 1-6, 1-6, 6-3, 6-7 (5) in two hours and 57 minutes.

On the other hand, Casper Ruud defeated Tommy Paul 7-6 (3), 6-7 (5), 7-6 (2), 5-7, 6-0 after a match that lasted at least four hours and 23 minutes

Nick Kyrgios and Daniil Medvedev also reached the round of 16 and will play against each other for a place in the quarterfinals at Flushing Meadows.

Andy Murray lost to Matteo Berrettini in the third round of the 2022 US Open 4-6, 4-6, 7-6 (1), 3-6.

US Open 2022, third round – results are registered on Friday

Daniil Medvedev (favorite 1) – Wu Yibin 6-4, 6-2, 6-2

Nick Kyrgios (23) – Jeffrey Wolfe 6-4, 6-2, 6-3

Pablo Carreño (12) – Alex De Minaur (18) 6-1, 6-1, 3-6, 7-6 (5)

Karen Khachanov (27) – Jack Draper 6-3, 4-6, 6-5 (Draper withdrew)

Alejandro Davidovich Fokina – Daniel Elahi Galan 6-4, 5-7, 6-4, 6-4

Matteo Berrettini (13) – Andy Murray 6-4, 6-4, 6-7 (1), 6-3

Corentin Muthe – Pedro Kachin 6-3, 4-6, 6-2, 7-5

Casper Ruud (5) – Tommy Paul (29) 7-6 (3), 6-7 (5), 7-6 (2), 5-7, 6-0.​